منابع مشابه
Mechanisms of vertebrate segmentation.
That all higher organisms possess some segmental organization during their development is presumably no coincidence. Segmentation appears to be an important developmental strategy with which to build and diversify different body regions. It can be studied at many levels, ranging from molecule and genome, through cells and their interactions, to morphogenesis and whole body pattern; and there is...
متن کاملVertebrate Segmentation: Lunatic Transcriptional Regulation
Vertebrate segmentation relies on a molecular oscillator, the segmentation clock, which controls the periodic expression of genes such as lunatic fringe in the presomitic mesoderm. Oscillations of lunatic fringe transcripts have now been shown to be controlled at the transcriptional level by clock elements in the lunatic fringe promoter.
متن کاملRecent advances in understanding vertebrate segmentation
Segmentation is the partitioning of the body axis into a series of repeating units or segments. This widespread body plan is found in annelids, arthropods, and chordates, showing it to be a successful developmental strategy for growing and generating diverse morphology and anatomy. Segmentation has been extensively studied over the years. Forty years ago, Cooke and Zeeman published the Clock an...
متن کاملBuilding the spine: the vertebrate segmentation clock.
One of the most striking characteristics of many animal and plant species is their organization in a series of periodically repeated anatomical modules. In animals, this particular patterning strategy of the body axis is termed segmentation, and it is observed in both vertebrates and invertebrates. Vertebrate segmentation has been associated with a molecular oscillator-the segmentation clock-wh...
متن کاملDelayed coupling theory of vertebrate segmentation.
Rhythmic and sequential subdivision of the elongating vertebrate embryonic body axis into morphological somites is controlled by an oscillating multicellular genetic network termed the segmentation clock. This clock operates in the presomitic mesoderm (PSM), generating dynamic stripe patterns of oscillatory gene-expression across the field of PSM cells. How these spatial patterns, the clock's c...
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ژورنال
عنوان ژورنال: Nature
سال: 1895
ISSN: 0028-0836,1476-4687
DOI: 10.1038/051367a0